Inflammatory nodular vascular diseases of the legs have been classified as severak distinctive entities based on their minor clinical and pathological variations. They have so many common features which often make the differential diagnosis difficult or impossible that reevaluation of these diseases is one of tie important problems:. in the dermatologic field.
The author studied the clinical and pathological relationship of those diseases in 36 patients including 70 cases of erythema nodosum, 7 of erythema induratum, 3 of panniculitis, and 6 of nodular vasculitis.
The results are as follows;
1. Erythema nodosum, erythema induratum and nodular vasculitis are most common: in the spring and patient are most often in their twenties
2. Common to all, females are more commonly affected than males.
3. Ervthema nodosum, erythema induratum and nodular vasculitis reveal no definite difference in their clinical pictures and laboratory fiz.sings.
4. Erythema nodosum, erythema induratum and nodular vasculitis are founded to, be associated with mostly streptococcal infection and/or tuberculosis; panniculitis. is associated mainly with streptococcal infection.
5. In histopathological findings, tubercle formation and casearion necrosis are more marked in erythema induratum than in erythema nodosum and nodular vasculitis.
6. The panniculitis is characterized by inflammation of the small sized vessels in subcutaneous tissues; Nodular vasculitis reveals its main lesion in the large sized vessels of lower dermis. In erythema nodosum and erythema induratum, small: and medium-sized vessels are involved in subcutaneous tissue.
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